STAT3 signaling drives EZH2 transcriptional activation and mediates poor prognosis in gastric cancer

BACKGROUND: STAT3 signaling plays the pivotal role in tumorigenesis through EZH2 epigenetic modification, which enhanced STAT3 activity by increased tyrosine phosphorylation of STAT3. Here, another possible feedback mechanism and clinical significance of EZH2 and STAT3 were investigated in gastric c...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Yuan-Ming, Wang, Cheng-Gang, Zhu, Min, Xing, Rui, Cui, Jian-Tao, Li, Wen-Mei, Yu, De-Dong, Wang, Shu-Bin, Zhu, Wei, Ye, Ying-Jiang, Wu, Yun, Wang, Shan, Lu, You-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148878/
https://www.ncbi.nlm.nih.gov/pubmed/27938379
http://dx.doi.org/10.1186/s12943-016-0561-z

Ejemplares similares

Ejemplares similares