Cargando…

Assessment of the Cytotoxic Effect of a Series of 1,4-Dihydropyridine Derivatives Against Human Cancer Cells

Cancer is a leading cause of death worldwide. Despite the availability of several chemotherapeutic drugs, there is still a great need for more efficient agents for a better management of cancer. In this contribution, a series of 11 1,4-dihydropyridines (1,4-DHPs) (4a, 4b and 7a-i) were synthesized a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Razzaghi-Asl, Nima, Miri, Ramin, Firuzi, Omidreza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shaheed Beheshti University of Medical Sciences 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149028/ https://www.ncbi.nlm.nih.gov/pubmed/27980576

Ejemplares similares

Novel 9-(alkylthio)-Acenaphtho[1,2-e]-1,2,4-triazine derivatives: synthesis, cytotoxic activity and molecular docking studies on B-cell lymphoma 2 (Bcl-2)
por: Mohammadi, Mohammad K, et al.
Publicado: (2014)

Searching for new cytotoxic agents based on chromen-4-one and chromane-2,4-dione scaffolds
por: Gaspar, Alexandra, et al.
Publicado: (2019)

Synthesis and Cytotoxicity Study of New Cyclopenta [b] quinoline-1,8-dione Derivatives
por: Miri, Ramin, et al.
Publicado: (2011)

Cytotoxic, Antioxidant and Antimicrobial Activities and Phenolic Contents of Eleven Salvia Species from Iran
por: Firuzi, Omidreza, et al.
Publicado: (2013)

Oxidative Aromatization, Cytotoxic Activity Evaluation and Conformational Study of Novel 7-aryl-10, 11-dihydro-7H-chromeno [4, 3-b]quinoline-6, 8(9H, 12H)-dione Derivatives.
por: Motamedi, Radineh, et al.
Publicado: (2014)

Cytotoxic Effect of Some 1, 4-Dihydropyridine Derivatives Containing Nitroimidazole Moiety
por: Miri, Ramin, et al.
Publicado: (2011)

Molecular Modeling of Indeno [1, 2-b] Quinoline-9, 11-Diones as Cytotoxic Agents
por: Miri, Ramin, et al.
Publicado: (2018)

Design and Synthesis of Novel 1-hydroxy-2,4,5-triaryl Imidazole Derivatives as Anti-cytokine Agents
por: Haghighijoo, Zahra, et al.
Publicado: (2020)

Novel Cytotoxic Phenanthro-triazine-3-thiol Derivatives as Potential DNA Intercalators and Bcl-2 Inhibitors
por: Khoshneviszadeh, Mehdi, et al.
Publicado: (2021)

Synthesis and Anticonvulsant Activity of a New Series of 1,4-Dihydropyridine Derivatives
por: Kumar, R. Surendra, et al.
Publicado: (2010)

Antimicrobial, anticoagulant, and cytotoxic evaluation of multidrug resistance of new 1,4-dihydropyridine derivatives
por: Ahamed, Anis, et al.
Publicado: (2018)

Intramolecular hydrogen bonds in 1,4-dihydropyridine derivatives
por: Petrova, M., et al.
Publicado: (2018)

Data for the cytotoxicity, self-assembling properties and synthesis of 4-pyridinium-1,4-dihydropyridines
por: Pajuste, Klavs, et al.
Publicado: (2020)

Ab-initio and Conformational Analysis of a Potent VEGFR-2 Inhibitor: A Case Study on Motesanib
por: Ebadi, Ahmad, et al.
Publicado: (2014)

Comparative amino acid decomposition analysis of potent type I p38α inhibitors
por: Ebadi, Ahmad, et al.
Publicado: (2013)

Novel 5-oxo-hexahydroquinoline derivatives: design, synthesis, in vitro P-glycoprotein-mediated multidrug resistance reversal profile and molecular dynamics simulation study
por: Shahraki, Omolbanin, et al.
Publicado: (2017)

Correction to ‘Intramolecular hydrogen bonds in 1,4-dihydropyridine derivatives’
por: Petrova, M., et al.
Publicado: (2018)

Novel 1,4-Dihydropyridine Derivatives as Mineralocorticoid Receptor Antagonists
por: Pérez-Gordillo, Felipe Luis, et al.
Publicado: (2023)

Antihypertensive effects of new dihydropyridine derivatives on phenylephrine-raised blood pressure in rats
por: Fard, Sara Rowghani Haghighi, et al.
Publicado: (2016)

Fragment-based Binding Efficiency Indices in Bioactive Molecular Design: A Computational Approach to BACE-1 Inhibitors
por: Razzaghi-Asl, Nima, et al.
Publicado: (2013)

Effect of Biomolecular Conformation on Docking Simulation: A Case Study on a Potent HIV-1 Protease Inhibitor
por: Razzaghi-Asl, Nima, et al.
Publicado: (2015)

Synthesis and cytotoxicity evaluation of novel cyclic/non-cyclic N-aryl enamino amides against human cancer cell lines
por: Bohlooli, Shahab, et al.
Publicado: (2020)

Diterpenoids from Roots of Salvia lachnocalyx; In-silico and In-vitro Toxicity against Human Cancer Cell Lines
por: Hadavand Mirzaei, Hossein, et al.
Publicado: (2020)

Comparison between 1,2-Dihydropyridine and 1,4-Dihydropyridine on Hydride-Donating Ability and Activity
por: Zhang, Jin-Ye, et al.
Publicado: (2022)

Synthesis and cloxacillin antimicrobial enhancement of 2-methylsulfonylimidazolyl-1,4-dihydropyridine derivatives
por: Akbarzadeh, T., et al.
Publicado: (2010)

First Organocatalytic Asymmetric Synthesis of 1-Benzamido-1,4-Dihydropyridine Derivatives
por: Auria-Luna, Fernando, et al.
Publicado: (2018)

Intramolecular C-H···O Hydrogen Bonding in 1,4-Dihydropyridine Derivatives
por: Petrova, Marina, et al.
Publicado: (2011)

Genotoxic and genoprotective effects of 1,4-dihydropyridine derivatives: a brief review
por: Leonova, Elina, et al.
Publicado: (2023)

Synthesis and cytotoxic effect of a few N-heteroaryl enamino amides and dihydropyrimidinethiones on AGS and MCF-7 human cancer cell lines
por: Tavangar, Sajjad, et al.
Publicado: (2020)

Effects of Omega-3 Polyunsaturated Fatty Acids on Heart Function and Oxidative Stress Biomarkers in Pediatric Patients with Dilated Cardiomyopathy
por: Firuzi, Omidreza, et al.
Publicado: (2013)

Synthesis, cytotoxic assessment, and molecular docking studies of 2,6-diaryl-substituted pyridine and 3,4- dihydropyrimidine-2(1H)-one scaffolds
por: HOSSEINZADEH, Zahra, et al.
Publicado: (2020)

Design, synthesis and evaluation of cytotoxic, antimicrobial, and anti-HIV-1 activities of new 1,2,3,4-tetrahydropyrimidine derivatives
por: Razzaghi-Asl, Nima, et al.
Publicado: (2019)

1,4-Dihydropyridine as a Promising Scaffold for Novel Antimicrobials Against Helicobacter pylori
por: González, Andrés, et al.
Publicado: (2022)

Phenanthrotriazine Derivatives Containing Arylidine Hydrazone Moieties as Novel Potential c-Met Inhibitors with Anticancer Effect
por: Edraki, Najmeh, et al.
Publicado: (2021)

1,4-Dihydropyridine Derivatives: Dihydronicotinamide Analogues—Model Compounds Targeting Oxidative Stress
por: Velena, Astrida, et al.
Publicado: (2016)

Antioxidative 1,4-Dihydropyridine Derivatives Modulate Oxidative Stress and Growth of Human Osteoblast-Like Cells In Vitro
por: Milkovic, Lidija, et al.
Publicado: (2018)

Direct Aminolysis of Ethoxycarbonylmethyl 1,4-Dihydropyridine-3-carboxylates
por: Vigante, Brigita, et al.
Publicado: (2015)

1,4-Dihydropyridine: synthetic advances, medicinal and insecticidal properties
por: A., Parthiban, et al.
Publicado: (2022)

Direct Enantiomeric Resolution of Seventeen Racemic 1,4-Dihydropyridine-Based Hexahydroquinoline Derivatives by HPLC
por: Sun, Jiayi, et al.
Publicado: (2019)

Calcined Layered Double Hydroxides: Catalysts for Xanthene, 1,4-Dihydropyridine, and Polyhydroquinoline Derivative Synthesis
por: Rathee, Garima, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_h3j9cttjvm6oc5gd0i3fjioeng