Some Biochemical Markers in Patients with Alzheimer’s Disease

BACKGROUND: Metal ions effect on homeostasis of Alzheimer’s disease (AD) patients. The aim of this study was to assess the metal ions (Iron, Zinc and Copper) and CBC in patients with AD in comparison with normal range. METHODS: The samples of study were 17 patients with AD in Tehran’s aging centers...

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Autores principales: KHANAHMADI, Mohammad, FARHUD, Dariush D., MALMIR, Maryam, ORANG, Soheila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2016
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149500/
https://www.ncbi.nlm.nih.gov/pubmed/27957443
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author KHANAHMADI, Mohammad
FARHUD, Dariush D.
MALMIR, Maryam
ORANG, Soheila
author_facet KHANAHMADI, Mohammad
FARHUD, Dariush D.
MALMIR, Maryam
ORANG, Soheila
author_sort KHANAHMADI, Mohammad
collection PubMed
description BACKGROUND: Metal ions effect on homeostasis of Alzheimer’s disease (AD) patients. The aim of this study was to assess the metal ions (Iron, Zinc and Copper) and CBC in patients with AD in comparison with normal range. METHODS: The samples of study were 17 patients with AD in Tehran’s aging centers in 2015, selected as an access sample. Blood samples were analyzed in a pathobiology laboratory. Data were analyzed by one sample t-test. RESULTS: According to the normal range, provided by laboratory, there is a significant difference between zinc in patients with AD and normal reference interval (α=0.01). The comparison of CBC of the AD patients with normal group showed also some decreases CONCLUSION: Zinc value in AD patients is significantly lower than normal range. It should be repeated by a larger sample size.
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spelling pubmed-51495002016-12-12 Some Biochemical Markers in Patients with Alzheimer’s Disease KHANAHMADI, Mohammad FARHUD, Dariush D. MALMIR, Maryam ORANG, Soheila Iran J Public Health Short Communication BACKGROUND: Metal ions effect on homeostasis of Alzheimer’s disease (AD) patients. The aim of this study was to assess the metal ions (Iron, Zinc and Copper) and CBC in patients with AD in comparison with normal range. METHODS: The samples of study were 17 patients with AD in Tehran’s aging centers in 2015, selected as an access sample. Blood samples were analyzed in a pathobiology laboratory. Data were analyzed by one sample t-test. RESULTS: According to the normal range, provided by laboratory, there is a significant difference between zinc in patients with AD and normal reference interval (α=0.01). The comparison of CBC of the AD patients with normal group showed also some decreases CONCLUSION: Zinc value in AD patients is significantly lower than normal range. It should be repeated by a larger sample size. Tehran University of Medical Sciences 2016-10 /pmc/articles/PMC5149500/ /pubmed/27957443 Text en Copyright© Iranian Public Health Association & Tehran University of Medical Sciences This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Short Communication
KHANAHMADI, Mohammad
FARHUD, Dariush D.
MALMIR, Maryam
ORANG, Soheila
Some Biochemical Markers in Patients with Alzheimer’s Disease
title Some Biochemical Markers in Patients with Alzheimer’s Disease
title_full Some Biochemical Markers in Patients with Alzheimer’s Disease
title_fullStr Some Biochemical Markers in Patients with Alzheimer’s Disease
title_full_unstemmed Some Biochemical Markers in Patients with Alzheimer’s Disease
title_short Some Biochemical Markers in Patients with Alzheimer’s Disease
title_sort some biochemical markers in patients with alzheimer’s disease
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149500/
https://www.ncbi.nlm.nih.gov/pubmed/27957443
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