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Granzymes A and K differentially potentiate LPS-induced cytokine response

Granzymes are serine proteases that, upon release from cytotoxic cells, induce apoptosis in tumor cells and virally infected cells. In addition, a role of granzymes in inflammation is emerging. Recently, we have demonstrated that extracellular granzyme K (GrK) potentiates lipopolysaccharide (LPS)-in...

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Detalles Bibliográficos
Autores principales:	Wensink, Annette C, Kok, Helena M, Meeldijk, Jan, Fermie, Job, Froelich, Christopher J, Hack, C Erik, Bovenschen, Niels
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149580/ https://www.ncbi.nlm.nih.gov/pubmed/28028441 http://dx.doi.org/10.1038/cddiscovery.2016.84

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