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Role and regulation of Cdc25A phosphatase in neuron death induced by NGF deprivation or β-amyloid
Neuron death during development and in Alzheimer’s disease (AD) is associated with aberrant regulation/induction of cell cycle proteins. However, the proximal events in this process are unknown. Cell cycle initiation requires dephosphorylation of cyclin-dependent kinases by cell division cycle 25A (...
Autores principales: | Chatterjee, Nandini, Sanphui, Priyankar, Kemeny, Stav, Greene, Lloyd A, Biswas, Subhas C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149581/ https://www.ncbi.nlm.nih.gov/pubmed/28028440 http://dx.doi.org/10.1038/cddiscovery.2016.83 |
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