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Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour
Inflammatory pseudotumours (IPT) are rare benign neoplasms of unknown aetiology. We present a case of hepatic IPT which was incidentally discovered in a patient with relapsed B-acute lymphoblastic leukaemia (B-ALL) undergoing pretransplant workup. After investigation to exclude an infective cause sh...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149620/ https://www.ncbi.nlm.nih.gov/pubmed/28018703 http://dx.doi.org/10.1155/2016/6801916 |
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author | de Mel, Sanjay Soe, Zarni Wong, Benjamin Ong, Ching Ching Teo, Lynette Tan, Lip Kun |
author_facet | de Mel, Sanjay Soe, Zarni Wong, Benjamin Ong, Ching Ching Teo, Lynette Tan, Lip Kun |
author_sort | de Mel, Sanjay |
collection | PubMed |
description | Inflammatory pseudotumours (IPT) are rare benign neoplasms of unknown aetiology. We present a case of hepatic IPT which was incidentally discovered in a patient with relapsed B-acute lymphoblastic leukaemia (B-ALL) undergoing pretransplant workup. After investigation to exclude an infective cause she underwent a reduced intensity conditioning stem cell transplant (SCT) successfully and currently remains well and in remission. On repeat liver MRI after SCT, the IPT was seen to be resolving. To the best of our knowledge this is the first report of an adult patient with hepatic IPT successfully undergoing SCT. The reduction in size of the IPT after SCT also suggests an inflammatory rather than an infective aetiology for IPT. |
format | Online Article Text |
id | pubmed-5149620 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-51496202016-12-25 Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour de Mel, Sanjay Soe, Zarni Wong, Benjamin Ong, Ching Ching Teo, Lynette Tan, Lip Kun Case Rep Transplant Case Report Inflammatory pseudotumours (IPT) are rare benign neoplasms of unknown aetiology. We present a case of hepatic IPT which was incidentally discovered in a patient with relapsed B-acute lymphoblastic leukaemia (B-ALL) undergoing pretransplant workup. After investigation to exclude an infective cause she underwent a reduced intensity conditioning stem cell transplant (SCT) successfully and currently remains well and in remission. On repeat liver MRI after SCT, the IPT was seen to be resolving. To the best of our knowledge this is the first report of an adult patient with hepatic IPT successfully undergoing SCT. The reduction in size of the IPT after SCT also suggests an inflammatory rather than an infective aetiology for IPT. Hindawi Publishing Corporation 2016 2016-11-28 /pmc/articles/PMC5149620/ /pubmed/28018703 http://dx.doi.org/10.1155/2016/6801916 Text en Copyright © 2016 Sanjay de Mel et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report de Mel, Sanjay Soe, Zarni Wong, Benjamin Ong, Ching Ching Teo, Lynette Tan, Lip Kun Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour |
title | Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour |
title_full | Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour |
title_fullStr | Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour |
title_full_unstemmed | Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour |
title_short | Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour |
title_sort | successful stem cell transplantation in a patient with pretransplant hepatic inflammatory pseudotumour |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149620/ https://www.ncbi.nlm.nih.gov/pubmed/28018703 http://dx.doi.org/10.1155/2016/6801916 |
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