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Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour

Inflammatory pseudotumours (IPT) are rare benign neoplasms of unknown aetiology. We present a case of hepatic IPT which was incidentally discovered in a patient with relapsed B-acute lymphoblastic leukaemia (B-ALL) undergoing pretransplant workup. After investigation to exclude an infective cause sh...

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Autores principales: de Mel, Sanjay, Soe, Zarni, Wong, Benjamin, Ong, Ching Ching, Teo, Lynette, Tan, Lip Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149620/
https://www.ncbi.nlm.nih.gov/pubmed/28018703
http://dx.doi.org/10.1155/2016/6801916
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author de Mel, Sanjay
Soe, Zarni
Wong, Benjamin
Ong, Ching Ching
Teo, Lynette
Tan, Lip Kun
author_facet de Mel, Sanjay
Soe, Zarni
Wong, Benjamin
Ong, Ching Ching
Teo, Lynette
Tan, Lip Kun
author_sort de Mel, Sanjay
collection PubMed
description Inflammatory pseudotumours (IPT) are rare benign neoplasms of unknown aetiology. We present a case of hepatic IPT which was incidentally discovered in a patient with relapsed B-acute lymphoblastic leukaemia (B-ALL) undergoing pretransplant workup. After investigation to exclude an infective cause she underwent a reduced intensity conditioning stem cell transplant (SCT) successfully and currently remains well and in remission. On repeat liver MRI after SCT, the IPT was seen to be resolving. To the best of our knowledge this is the first report of an adult patient with hepatic IPT successfully undergoing SCT. The reduction in size of the IPT after SCT also suggests an inflammatory rather than an infective aetiology for IPT.
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spelling pubmed-51496202016-12-25 Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour de Mel, Sanjay Soe, Zarni Wong, Benjamin Ong, Ching Ching Teo, Lynette Tan, Lip Kun Case Rep Transplant Case Report Inflammatory pseudotumours (IPT) are rare benign neoplasms of unknown aetiology. We present a case of hepatic IPT which was incidentally discovered in a patient with relapsed B-acute lymphoblastic leukaemia (B-ALL) undergoing pretransplant workup. After investigation to exclude an infective cause she underwent a reduced intensity conditioning stem cell transplant (SCT) successfully and currently remains well and in remission. On repeat liver MRI after SCT, the IPT was seen to be resolving. To the best of our knowledge this is the first report of an adult patient with hepatic IPT successfully undergoing SCT. The reduction in size of the IPT after SCT also suggests an inflammatory rather than an infective aetiology for IPT. Hindawi Publishing Corporation 2016 2016-11-28 /pmc/articles/PMC5149620/ /pubmed/28018703 http://dx.doi.org/10.1155/2016/6801916 Text en Copyright © 2016 Sanjay de Mel et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
de Mel, Sanjay
Soe, Zarni
Wong, Benjamin
Ong, Ching Ching
Teo, Lynette
Tan, Lip Kun
Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour
title Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour
title_full Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour
title_fullStr Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour
title_full_unstemmed Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour
title_short Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour
title_sort successful stem cell transplantation in a patient with pretransplant hepatic inflammatory pseudotumour
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149620/
https://www.ncbi.nlm.nih.gov/pubmed/28018703
http://dx.doi.org/10.1155/2016/6801916
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