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Skin Aging-Dependent Activation of the PI3K Signaling Pathway via Downregulation of PTEN Increases Intracellular ROS in Human Dermal Fibroblasts

Reactive oxygen species (ROS) play a major role in both chronological aging and photoaging. ROS induce skin aging through their damaging effect on cellular constituents. However, the origins of ROS have not been fully elucidated. We investigated that ROS generation of replicative senescent fibroblas...

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Detalles Bibliográficos
Autores principales:	Noh, Eun-Mi, Park, Jinny, Song, Hwa-Ryung, Kim, Jeong-Mi, Lee, Minok, Song, Hyun-Kyung, Hong, On-Yu, Whang, Pyoung H., Han, Myung-Kwan, Kwon, Kang-Beom, Kim, Jong-Suk, Lee, Young-Rae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149682/ https://www.ncbi.nlm.nih.gov/pubmed/28003865 http://dx.doi.org/10.1155/2016/6354261

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