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Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins

The nucleotidyl cyclase toxin ExoY is one of the virulence factors injected by the Pseudomonas aeruginosa type III secretion system into host cells. Inside cells, it is activated by an unknown eukaryotic cofactor to synthesize various cyclic nucleotide monophosphates. ExoY-like adenylate cyclases ar...

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Detalles Bibliográficos
Autores principales:	Belyy, Alexander, Raoux-Barbot, Dorothée, Saveanu, Cosmin, Namane, Abdelkader, Ogryzko, Vasily, Worpenberg, Lina, David, Violaine, Henriot, Veronique, Fellous, Souad, Merrifield, Christien, Assayag, Elodie, Ladant, Daniel, Renault, Louis, Mechold, Undine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150216/ https://www.ncbi.nlm.nih.gov/pubmed/27917880 http://dx.doi.org/10.1038/ncomms13582

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