SCN4B acts as a metastasis-suppressor gene preventing hyperactivation of cell migration in breast cancer

The development of metastases largely relies on the capacity of cancer cells to invade extracellular matrices (ECM) using two invasion modes termed ‘mesenchymal' and ‘amoeboid', with possible transitions between these modes. Here we show that the SCN4B gene, encoding for the β4 protein, in...

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Detalles Bibliográficos
Autores principales: Bon, Emeline, Driffort, Virginie, Gradek, Frédéric, Martinez-Caceres, Carlos, Anchelin, Monique, Pelegrin, Pablo, Cayuela, Maria-Luisa, Marionneau-Lambot, Séverine, Oullier, Thibauld, Guibon, Roseline, Fromont, Gaëlle, Gutierrez-Pajares, Jorge L., Domingo, Isabelle, Piver, Eric, Moreau, Alain, Burlaud-Gaillard, Julien, Frank, Philippe G., Chevalier, Stéphan, Besson, Pierre, Roger, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150224/
https://www.ncbi.nlm.nih.gov/pubmed/27917859
http://dx.doi.org/10.1038/ncomms13648

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