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Interleukin-37 Enhances the Suppressive Activity of Naturally Occurring CD4(+)CD25(+) Regulatory T Cells

Naturally occurring CD4(+)CD25(+) regulatory T cells (Tregs) are essential for the suppression of autoimmunity and can control the immune-mediated pathology during the early phase of sepsis. Our previous data showed that silencing interleukin-37 (IL-37) in human CD4(+)CD25(+) Tregs obviously reduced...

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Detalles Bibliográficos
Autores principales: Wang, Da-Wei, Dong, Ning, Wu, Yao, Zhu, Xiao-Mei, Wang, Chun-Ting, Yao, Yong-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150235/
https://www.ncbi.nlm.nih.gov/pubmed/27941849
http://dx.doi.org/10.1038/srep38955

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