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G-rich DNA-induced stress response blocks type-I-IFN but not CXCL10 secretion in monocytes
Excessive inflammation can cause damage to host cells and tissues. Thus, the secretion of inflammatory cytokines is tightly regulated at transcriptional, post-transcriptional and post-translational levels and influenced by cellular stress responses, such as endoplasmic reticulum (ER) stress or apopt...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150577/ https://www.ncbi.nlm.nih.gov/pubmed/27941826 http://dx.doi.org/10.1038/srep38405 |