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Isolated pores dissected from human two-pore channel 2 are functional

Multi-domain voltage-gated ion channels appear to have evolved through sequential rounds of intragenic duplication from a primordial one-domain precursor. Whereas modularity within one-domain symmetrical channels is established, little is known about the roles of individual regions within more compl...

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Detalles Bibliográficos
Autores principales:	Penny, Christopher J., Rahman, Taufiq, Sula, Altin, Miles, Andrew J., Wallace, B. A., Patel, Sandip
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150636/ https://www.ncbi.nlm.nih.gov/pubmed/27941820 http://dx.doi.org/10.1038/srep38426

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