Tissue-engineered 3-dimensional (3D) microenvironment enhances the direct reprogramming of fibroblasts into cardiomyocytes by microRNAs

We have recently shown that a combination of microRNAs, miR combo, can directly reprogram cardiac fibroblasts into functional cardiomyocytes in vitro and in vivo. Reprogramming of cardiac fibroblasts by miR combo in vivo is associated with improved cardiac function following myocardial infarction. H...

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Detalles Bibliográficos
Autores principales: Li, Yanzhen, Dal-Pra, Sophie, Mirotsou, Maria, Jayawardena, Tilanthi M., Hodgkinson, Conrad P., Bursac, Nenad, Dzau, Victor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150639/
https://www.ncbi.nlm.nih.gov/pubmed/27941896
http://dx.doi.org/10.1038/srep38815

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