Mature IgM-expressing plasma cells sense antigen and develop competence for cytokine production upon antigenic challenge

Dogma holds that plasma cells, as opposed to B cells, cannot bind antigen because they have switched from expression of membrane-bound immunoglobulins (Ig) that constitute the B-cell receptor (BCR) to production of the secreted form of immunoglobulins. Here we compare the phenotypical and functional...

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Detalles Bibliográficos
Autores principales: Blanc, Pascal, Moro-Sibilot, Ludovic, Barthly, Lucas, Jagot, Ferdinand, This, Sébastien, de Bernard, Simon, Buffat, Laurent, Dussurgey, Sébastien, Colisson, Renaud, Hobeika, Elias, Fest, Thierry, Taillardet, Morgan, Thaunat, Olivier, Sicard, Antoine, Mondière, Paul, Genestier, Laurent, Nutt, Stephen L., Defrance, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150646/
https://www.ncbi.nlm.nih.gov/pubmed/27924814
http://dx.doi.org/10.1038/ncomms13600

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