Cargando…

Clinical Predictors of Neurological Outcome within 72 h after Traumatic Cervical Spinal Cord Injury

To investigate the prognostic values of clinical factors 72 h within traumatic cervical spinal cord injury (TCSCI). Data were extracted from the medical materials of 57 TCSCI cases. AIS was used as the outcome measure and divided into dichotomous variables by two methods, i.e. “complete(AIS = A)/inc...

Descripción completa

Detalles Bibliográficos
Autores principales: Qiu, Zhi, Wang, Fangyong, Hong, Yi, Zhang, Junwei, Tang, Hehu, Li, Xiang, Jiang, Shudong, Lv, Zhen, Liu, Shujia, Chen, Shizheng, Liu, Jiesheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150991/
https://www.ncbi.nlm.nih.gov/pubmed/27941855
http://dx.doi.org/10.1038/srep38909
_version_ 1782474302115807232
author Qiu, Zhi
Wang, Fangyong
Hong, Yi
Zhang, Junwei
Tang, Hehu
Li, Xiang
Jiang, Shudong
Lv, Zhen
Liu, Shujia
Chen, Shizheng
Liu, Jiesheng
author_facet Qiu, Zhi
Wang, Fangyong
Hong, Yi
Zhang, Junwei
Tang, Hehu
Li, Xiang
Jiang, Shudong
Lv, Zhen
Liu, Shujia
Chen, Shizheng
Liu, Jiesheng
author_sort Qiu, Zhi
collection PubMed
description To investigate the prognostic values of clinical factors 72 h within traumatic cervical spinal cord injury (TCSCI). Data were extracted from the medical materials of 57 TCSCI cases. AIS was used as the outcome measure and divided into dichotomous variables by two methods, i.e. “complete(AIS = A)/incomplete(AIS ≠ A) SCI” and “motor complete(AIS = A or B)/incomplete(AIS ≠ A and B) SCI”. Relationships between evaluated factors and outcomes were investigated by univariate and multivariate methods. MRI Cord transection (MCT) cases, most significantly related to complete SCIs by univariate analysis (P = 0.006), all showed complete SCIs when discharged, which makes it unsuitable for logistic regression. With MCT cases removed, univariate analysis was conducted again, then logistic regression. At last, only C5 spine injury (P = 0.024, OR = 0.241) was related to complete SCI. Cases with compression flexion injury mechanism (CFIM), most significantly related to motor complete SCIs by univariate analysis (P = 0.001), was also unsuitable for logistic regression for the same reason. At last, C3 spine injury (P = 0.033, OR = 0.068) and high energy injury (P = 0.033, OR = 14.763) were related to motor complete SCIs with CFIM cases removed. The results show that MCT and C5 spine injury are good predictors for complete/incomplete SCIs. CFIM, C3 spine injury and high energy injury are good predictors for motor complete/incomplete SCIs.
format Online
Article
Text
id pubmed-5150991
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-51509912016-12-19 Clinical Predictors of Neurological Outcome within 72 h after Traumatic Cervical Spinal Cord Injury Qiu, Zhi Wang, Fangyong Hong, Yi Zhang, Junwei Tang, Hehu Li, Xiang Jiang, Shudong Lv, Zhen Liu, Shujia Chen, Shizheng Liu, Jiesheng Sci Rep Article To investigate the prognostic values of clinical factors 72 h within traumatic cervical spinal cord injury (TCSCI). Data were extracted from the medical materials of 57 TCSCI cases. AIS was used as the outcome measure and divided into dichotomous variables by two methods, i.e. “complete(AIS = A)/incomplete(AIS ≠ A) SCI” and “motor complete(AIS = A or B)/incomplete(AIS ≠ A and B) SCI”. Relationships between evaluated factors and outcomes were investigated by univariate and multivariate methods. MRI Cord transection (MCT) cases, most significantly related to complete SCIs by univariate analysis (P = 0.006), all showed complete SCIs when discharged, which makes it unsuitable for logistic regression. With MCT cases removed, univariate analysis was conducted again, then logistic regression. At last, only C5 spine injury (P = 0.024, OR = 0.241) was related to complete SCI. Cases with compression flexion injury mechanism (CFIM), most significantly related to motor complete SCIs by univariate analysis (P = 0.001), was also unsuitable for logistic regression for the same reason. At last, C3 spine injury (P = 0.033, OR = 0.068) and high energy injury (P = 0.033, OR = 14.763) were related to motor complete SCIs with CFIM cases removed. The results show that MCT and C5 spine injury are good predictors for complete/incomplete SCIs. CFIM, C3 spine injury and high energy injury are good predictors for motor complete/incomplete SCIs. Nature Publishing Group 2016-12-12 /pmc/articles/PMC5150991/ /pubmed/27941855 http://dx.doi.org/10.1038/srep38909 Text en Copyright © 2016, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Qiu, Zhi
Wang, Fangyong
Hong, Yi
Zhang, Junwei
Tang, Hehu
Li, Xiang
Jiang, Shudong
Lv, Zhen
Liu, Shujia
Chen, Shizheng
Liu, Jiesheng
Clinical Predictors of Neurological Outcome within 72 h after Traumatic Cervical Spinal Cord Injury
title Clinical Predictors of Neurological Outcome within 72 h after Traumatic Cervical Spinal Cord Injury
title_full Clinical Predictors of Neurological Outcome within 72 h after Traumatic Cervical Spinal Cord Injury
title_fullStr Clinical Predictors of Neurological Outcome within 72 h after Traumatic Cervical Spinal Cord Injury
title_full_unstemmed Clinical Predictors of Neurological Outcome within 72 h after Traumatic Cervical Spinal Cord Injury
title_short Clinical Predictors of Neurological Outcome within 72 h after Traumatic Cervical Spinal Cord Injury
title_sort clinical predictors of neurological outcome within 72 h after traumatic cervical spinal cord injury
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150991/
https://www.ncbi.nlm.nih.gov/pubmed/27941855
http://dx.doi.org/10.1038/srep38909
work_keys_str_mv AT qiuzhi clinicalpredictorsofneurologicaloutcomewithin72haftertraumaticcervicalspinalcordinjury
AT wangfangyong clinicalpredictorsofneurologicaloutcomewithin72haftertraumaticcervicalspinalcordinjury
AT hongyi clinicalpredictorsofneurologicaloutcomewithin72haftertraumaticcervicalspinalcordinjury
AT zhangjunwei clinicalpredictorsofneurologicaloutcomewithin72haftertraumaticcervicalspinalcordinjury
AT tanghehu clinicalpredictorsofneurologicaloutcomewithin72haftertraumaticcervicalspinalcordinjury
AT lixiang clinicalpredictorsofneurologicaloutcomewithin72haftertraumaticcervicalspinalcordinjury
AT jiangshudong clinicalpredictorsofneurologicaloutcomewithin72haftertraumaticcervicalspinalcordinjury
AT lvzhen clinicalpredictorsofneurologicaloutcomewithin72haftertraumaticcervicalspinalcordinjury
AT liushujia clinicalpredictorsofneurologicaloutcomewithin72haftertraumaticcervicalspinalcordinjury
AT chenshizheng clinicalpredictorsofneurologicaloutcomewithin72haftertraumaticcervicalspinalcordinjury
AT liujiesheng clinicalpredictorsofneurologicaloutcomewithin72haftertraumaticcervicalspinalcordinjury