Allorecognition of HLA-C Mismatches by CD8(+) T Cells in Hematopoietic Stem Cell Transplantation Is a Complex Interplay between Mismatched Peptide-Binding Region Residues, HLA-C Expression, and HLA-DPB1 Disparities

HLA-C locus mismatches (MMs) are the most frequent class I disparities in unrelated hematopoietic stem cell transplantation (HSCT) and have a detrimental impact on clinical outcome. Recently, a few retrospective clinical studies have reported some variability in the immunogenicity of HLA-C incompati...

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Detalles Bibliográficos
Autores principales: Bettens, Florence, Buhler, Stéphane, Tiercy, Jean-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5151176/
https://www.ncbi.nlm.nih.gov/pubmed/28018351
http://dx.doi.org/10.3389/fimmu.2016.00584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5151176/
https://www.ncbi.nlm.nih.gov/pubmed/28018351
http://dx.doi.org/10.3389/fimmu.2016.00584

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