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Growth Differentiation Factor-15–Induced Contractile Activity and Extracellular Matrix Production in Human Trabecular Meshwork Cells
PURPOSE: To determine the role and regulation of growth differentiation factor-15 (GDF-15), a TGF-β–related cytokine in human trabecular meshwork (TM) cells in the context of aqueous humor (AH) outflow and IOP. METHODS: Regulation of expression by external cues, and the distribution and secretion of...
Autores principales: | Muralidharan, Arumugam Ramachandran, Maddala, Rupalatha, Skiba, Nikolai P., Rao, Ponugoti Vasantha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5152563/ https://www.ncbi.nlm.nih.gov/pubmed/27918822 http://dx.doi.org/10.1167/iovs.16-20671 |
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