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The CHRNA5–A3–B4 Gene Cluster and Smoking: From Discovery to Therapeutics

Genome-wide association studies (GWASs) have identified associations between the CHRNA5–CHRNA3–CHRNB4 gene cluster and smoking heaviness and nicotine dependence. Studies in rodents have described the anatomical localisation and function of the nicotinic acetylcholine receptors (nAChRs) formed by the...

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Detalles Bibliográficos
Autores principales:	Lassi, Glenda, Taylor, Amy E., Timpson, Nicholas J., Kenny, Paul J., Mather, Robert J., Eisen, Tim, Munafò, Marcus R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Applied Science Publishing 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5152594/ https://www.ncbi.nlm.nih.gov/pubmed/27871728 http://dx.doi.org/10.1016/j.tins.2016.10.005

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