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Limited Impact of Imatinib in a Murine Model of Sclerodermatous Chronic Graft-versus-Host Disease

BACKGROUND: Sclerodermatous chronic Graft-versus-Host Disease (scl-cGVHD) is one of the most severe form of cGVHD. The Platelet-derived Grotwth Factor (PDGF) and the Transforming Growth Factor-β (TGF-β) play a significant role in the fibrosing process occurring in scl-cGVHD. This prompted us to asse...

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Detalles Bibliográficos
Autores principales:	Belle, Ludovic, Fransolet, Gilles, Somja, Joan, Binsfeld, Marilène, Delvenne, Philippe, Drion, Pierre, Hannon, Muriel, Beguin, Yves, Ehx, Grégory, Baron, Frédéric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5152855/ https://www.ncbi.nlm.nih.gov/pubmed/27942010 http://dx.doi.org/10.1371/journal.pone.0167997

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