Hydroxycholesterol Levels in the Serum and Cerebrospinal Fluid of Patients with Neuromyelitis Optica Revealed by LC-Ag(+)CIS/MS/MS and LC-ESI/MS/MS with Picolinic Derivatization: Increased Levels and Association with Disability during Acute Attack

Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system (CNS). Hydroxycholesterols (OHCs), metabolites of CNS cholesterol, are involved in diverse cellular responses to inflammation and demyelination, and may also be involved in the pathogenesis of NMO. We a...

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Detalles Bibliográficos
Autores principales: Cha, Eunju, Lee, Kang Mi, Park, Ki Duk, Park, Kyung Seok, Lee, Kwang-Woo, Kim, Sung-Min, Lee, Jaeick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5152860/
https://www.ncbi.nlm.nih.gov/pubmed/27942009
http://dx.doi.org/10.1371/journal.pone.0167819

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