The latent cytomegalovirus decreases telomere length by microcompetition

Reduced telomere length has been associated with aging and age-related diseases. Latent infection with the Cytomegalovirus (CMV) induces telomere shortening in the infected cells. Latent CMV infection may cause reduced telomere length via GABP transcription factor deficiency, according to the Microc...

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Detalles Bibliográficos
Autores principales: Polansky, Hanan, Javaherian, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter Open 2015
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5152988/
https://www.ncbi.nlm.nih.gov/pubmed/28352708
http://dx.doi.org/10.1515/med-2015-0042
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author Polansky, Hanan
Javaherian, Adrian
author_facet Polansky, Hanan
Javaherian, Adrian
author_sort Polansky, Hanan
collection PubMed
description Reduced telomere length has been associated with aging and age-related diseases. Latent infection with the Cytomegalovirus (CMV) induces telomere shortening in the infected cells. Latent CMV infection may cause reduced telomere length via GABP transcription factor deficiency, according to the Microcompetition Theory. Microcompetition and viral-induced transcription factor deficiency is important since most people harbor a latent viral infection.
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spelling pubmed-51529882017-03-28 The latent cytomegalovirus decreases telomere length by microcompetition Polansky, Hanan Javaherian, Adrian Open Med (Wars) Commentary Reduced telomere length has been associated with aging and age-related diseases. Latent infection with the Cytomegalovirus (CMV) induces telomere shortening in the infected cells. Latent CMV infection may cause reduced telomere length via GABP transcription factor deficiency, according to the Microcompetition Theory. Microcompetition and viral-induced transcription factor deficiency is important since most people harbor a latent viral infection. De Gruyter Open 2015-05-27 /pmc/articles/PMC5152988/ /pubmed/28352708 http://dx.doi.org/10.1515/med-2015-0042 Text en © 2015 Hanan Polansky, Adrian Javaherian http://creativecommons.org/licenses/by-nc-nd/3.0 This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.
spellingShingle Commentary
Polansky, Hanan
Javaherian, Adrian
The latent cytomegalovirus decreases telomere length by microcompetition
title The latent cytomegalovirus decreases telomere length by microcompetition
title_full The latent cytomegalovirus decreases telomere length by microcompetition
title_fullStr The latent cytomegalovirus decreases telomere length by microcompetition
title_full_unstemmed The latent cytomegalovirus decreases telomere length by microcompetition
title_short The latent cytomegalovirus decreases telomere length by microcompetition
title_sort latent cytomegalovirus decreases telomere length by microcompetition
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5152988/
https://www.ncbi.nlm.nih.gov/pubmed/28352708
http://dx.doi.org/10.1515/med-2015-0042
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