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G9a inhibits CREB-triggered expression of mu opioid receptor in primary sensory neurons following peripheral nerve injury
Neuropathic pain, a distressing and debilitating disorder, is still poorly managed in clinic. Opioids, like morphine, remain the mainstay of prescribed medications in the treatment of this disorder, but their analgesic effects are highly unsatisfactory in part due to nerve injury-induced reduction o...
Autores principales: | Liang, Lingli, Zhao, Jian-Yuan, Gu, Xiyao, Wu, Shaogen, Mo, Kai, Xiong, Ming, Marie Lutz, Brianna, Bekker, Alex, Tao, Yuan-Xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153028/ https://www.ncbi.nlm.nih.gov/pubmed/27927796 http://dx.doi.org/10.1177/1744806916682242 |
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