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Clinical effects of prior trastuzumab on combination eribulin mesylate plus trastuzumab as first-line treatment for human epidermal growth factor receptor 2 positive locally recurrent or metastatic breast cancer: results from a Phase II, single-arm, multicenter study
Eribulin mesylate, a novel nontaxane microtubule dynamics inhibitor in the halichondrin class of antineoplastic drugs, is indicated for the treatment of patients with metastatic breast cancer who previously received ≥2 chemotherapy regimens in the metastatic setting. Primary data from a Phase II tri...
Autores principales: | Puhalla, Shannon, Wilks, Sharon, Brufsky, Adam M, O’Shaughnessy, Joyce, Schwartzberg, Lee S, Berrak, Erhan, Song, James, Vahdat, Linda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153255/ https://www.ncbi.nlm.nih.gov/pubmed/27994483 http://dx.doi.org/10.2147/BCTT.S98696 |
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