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The nasal delivery of nanoencapsulated statins – an approach for brain delivery
PURPOSE: Along with their cholesterol-lowering effect, statins have shown a wide range of pleiotropic effects potentially beneficial to neurodegenerative diseases. However, such effects are extremely elusive via the conventional oral administration. The purpose of the present study was to prepare an...
Autores principales: | Clementino, Adryana, Batger, Mellissa, Garrastazu, Gabriela, Pozzoli, Michele, Del Favero, Elena, Rondelli, Valeria, Gutfilen, Bianca, Barboza, Thiago, Sukkar, Maria B, Souza, Sergio A L, Cantù, Laura, Sonvico, Fabio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153258/ https://www.ncbi.nlm.nih.gov/pubmed/27994459 http://dx.doi.org/10.2147/IJN.S119033 |
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