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Comparison of oral absorption models for pregabalin: usefulness of transit compartment model
Pregabalin is an anticonvulsant used for the treatment of neuropathic pain and partial seizure in adults. The aim of this study was to develop a population pharmacokinetic (PK) model to describe the absorption characteristics of pregabalin given fasted or after meals. Data from five healthy subject...
Autores principales: | Hong, Taegon, Han, Seunghoon, Lee, Jongtae, Jeon, Sangil, Yim, Dong-Seok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153293/ https://www.ncbi.nlm.nih.gov/pubmed/27994441 http://dx.doi.org/10.2147/DDDT.S123318 |
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