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Pharmacokinetic modeling of a novel hypoxia PET tracer [(18)F]HX4 in patients with non-small cell lung cancer

BACKGROUND: [(18)F]HX4 is a promising new PET tracer developed to identify hypoxic areas in tumor tissue. This study analyzes [(18)F]HX4 kinetics and assesses the performance of simplified methods for quantification of [(18)F]HX4 uptake. To this end, eight patients with non-small cell lung cancer re...

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Detalles Bibliográficos
Autores principales:	Verwer, E. E., Zegers, C. M. L., van Elmpt, W., Wierts, R., Windhorst, A. D., Mottaghy, F. M., Lambin, P., Boellaard, R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153396/ https://www.ncbi.nlm.nih.gov/pubmed/27957730 http://dx.doi.org/10.1186/s40658-016-0167-y

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