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Higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: Result from AHAP Study
BACKGROUND: Aspirin is the most widely used drug in medicine for cardiovascular and as recently for its role in cancer prevention. Although the risk of bleeding events increased following regular use of aspirin, little is known about the association of aspirin and hematuria. The present study aimed...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Babol University of Medical Sciences
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153520/ https://www.ncbi.nlm.nih.gov/pubmed/27999646 |
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author | Moudi, Emadouddin Hosseini, Seyed-Reza Bijani, Ali |
author_facet | Moudi, Emadouddin Hosseini, Seyed-Reza Bijani, Ali |
author_sort | Moudi, Emadouddin |
collection | PubMed |
description | BACKGROUND: Aspirin is the most widely used drug in medicine for cardiovascular and as recently for its role in cancer prevention. Although the risk of bleeding events increased following regular use of aspirin, little is known about the association of aspirin and hematuria. The present study aimed to evaluate the association of regular aspirin use and microscopic hematuria in elderly. METHODS: In this study, we have extracted the data of elderly people who participated in Amirkola Health and Aging Project (AHAP) and taking regular doses of aspirin. The prevalence of microscopic hematuria was compared between the elderly who took aspirin regularly and those who did not take it. RESULTS: A total of 1243 individuals (54.22% males, 45.78% females) were entered in to the study. Two hundred and eighty-four (23%) elderly took regular doses of aspirin. Microscopic hematuria was seen in 305 (24.54%) elderly. The prevalence of microscopic hematuria was 27.27% in regular users of aspirin and 23.72% in non-users of aspirin (P=0.126). The prevalence of microscopic hematuria was significantly higher among the regular users of aspirin compared to non-users in multiple logistic regression analysis (P=0.035, OR=1.40, 95%CI: 1.02-1.92). CONCLUSION: Taking regular doses of aspirin was accompanied with higher rate of microscopic hematuria in the elderly. |
format | Online Article Text |
id | pubmed-5153520 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Babol University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-51535202016-12-20 Higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: Result from AHAP Study Moudi, Emadouddin Hosseini, Seyed-Reza Bijani, Ali Caspian J Intern Med Original Article BACKGROUND: Aspirin is the most widely used drug in medicine for cardiovascular and as recently for its role in cancer prevention. Although the risk of bleeding events increased following regular use of aspirin, little is known about the association of aspirin and hematuria. The present study aimed to evaluate the association of regular aspirin use and microscopic hematuria in elderly. METHODS: In this study, we have extracted the data of elderly people who participated in Amirkola Health and Aging Project (AHAP) and taking regular doses of aspirin. The prevalence of microscopic hematuria was compared between the elderly who took aspirin regularly and those who did not take it. RESULTS: A total of 1243 individuals (54.22% males, 45.78% females) were entered in to the study. Two hundred and eighty-four (23%) elderly took regular doses of aspirin. Microscopic hematuria was seen in 305 (24.54%) elderly. The prevalence of microscopic hematuria was 27.27% in regular users of aspirin and 23.72% in non-users of aspirin (P=0.126). The prevalence of microscopic hematuria was significantly higher among the regular users of aspirin compared to non-users in multiple logistic regression analysis (P=0.035, OR=1.40, 95%CI: 1.02-1.92). CONCLUSION: Taking regular doses of aspirin was accompanied with higher rate of microscopic hematuria in the elderly. Babol University of Medical Sciences 2016 /pmc/articles/PMC5153520/ /pubmed/27999646 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Moudi, Emadouddin Hosseini, Seyed-Reza Bijani, Ali Higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: Result from AHAP Study |
title | Higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: Result from AHAP Study |
title_full | Higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: Result from AHAP Study |
title_fullStr | Higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: Result from AHAP Study |
title_full_unstemmed | Higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: Result from AHAP Study |
title_short | Higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: Result from AHAP Study |
title_sort | higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: result from ahap study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153520/ https://www.ncbi.nlm.nih.gov/pubmed/27999646 |
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