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Higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: Result from AHAP Study

BACKGROUND: Aspirin is the most widely used drug in medicine for cardiovascular and as recently for its role in cancer prevention. Although the risk of bleeding events increased following regular use of aspirin, little is known about the association of aspirin and hematuria. The present study aimed...

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Autores principales: Moudi, Emadouddin, Hosseini, Seyed-Reza, Bijani, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Babol University of Medical Sciences 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153520/
https://www.ncbi.nlm.nih.gov/pubmed/27999646
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author Moudi, Emadouddin
Hosseini, Seyed-Reza
Bijani, Ali
author_facet Moudi, Emadouddin
Hosseini, Seyed-Reza
Bijani, Ali
author_sort Moudi, Emadouddin
collection PubMed
description BACKGROUND: Aspirin is the most widely used drug in medicine for cardiovascular and as recently for its role in cancer prevention. Although the risk of bleeding events increased following regular use of aspirin, little is known about the association of aspirin and hematuria. The present study aimed to evaluate the association of regular aspirin use and microscopic hematuria in elderly. METHODS: In this study, we have extracted the data of elderly people who participated in Amirkola Health and Aging Project (AHAP) and taking regular doses of aspirin. The prevalence of microscopic hematuria was compared between the elderly who took aspirin regularly and those who did not take it. RESULTS: A total of 1243 individuals (54.22% males, 45.78% females) were entered in to the study. Two hundred and eighty-four (23%) elderly took regular doses of aspirin. Microscopic hematuria was seen in 305 (24.54%) elderly. The prevalence of microscopic hematuria was 27.27% in regular users of aspirin and 23.72% in non-users of aspirin (P=0.126). The prevalence of microscopic hematuria was significantly higher among the regular users of aspirin compared to non-users in multiple logistic regression analysis (P=0.035, OR=1.40, 95%CI: 1.02-1.92). CONCLUSION: Taking regular doses of aspirin was accompanied with higher rate of microscopic hematuria in the elderly.
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spelling pubmed-51535202016-12-20 Higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: Result from AHAP Study Moudi, Emadouddin Hosseini, Seyed-Reza Bijani, Ali Caspian J Intern Med Original Article BACKGROUND: Aspirin is the most widely used drug in medicine for cardiovascular and as recently for its role in cancer prevention. Although the risk of bleeding events increased following regular use of aspirin, little is known about the association of aspirin and hematuria. The present study aimed to evaluate the association of regular aspirin use and microscopic hematuria in elderly. METHODS: In this study, we have extracted the data of elderly people who participated in Amirkola Health and Aging Project (AHAP) and taking regular doses of aspirin. The prevalence of microscopic hematuria was compared between the elderly who took aspirin regularly and those who did not take it. RESULTS: A total of 1243 individuals (54.22% males, 45.78% females) were entered in to the study. Two hundred and eighty-four (23%) elderly took regular doses of aspirin. Microscopic hematuria was seen in 305 (24.54%) elderly. The prevalence of microscopic hematuria was 27.27% in regular users of aspirin and 23.72% in non-users of aspirin (P=0.126). The prevalence of microscopic hematuria was significantly higher among the regular users of aspirin compared to non-users in multiple logistic regression analysis (P=0.035, OR=1.40, 95%CI: 1.02-1.92). CONCLUSION: Taking regular doses of aspirin was accompanied with higher rate of microscopic hematuria in the elderly. Babol University of Medical Sciences 2016 /pmc/articles/PMC5153520/ /pubmed/27999646 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Moudi, Emadouddin
Hosseini, Seyed-Reza
Bijani, Ali
Higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: Result from AHAP Study
title Higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: Result from AHAP Study
title_full Higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: Result from AHAP Study
title_fullStr Higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: Result from AHAP Study
title_full_unstemmed Higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: Result from AHAP Study
title_short Higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: Result from AHAP Study
title_sort higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: result from ahap study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153520/
https://www.ncbi.nlm.nih.gov/pubmed/27999646
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