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Oncogenic mutations and dysregulated pathways in obesity-associated hepatocellular carcinoma

Epidemiological studies showed that obesity and its related non-alcoholic fatty liver disease (NAFLD) promote hepatocellular carcinoma (HCC) development. We aimed to uncover the genetic alterations of NAFLD-HCC using whole-exome sequencing. We compared HCC development in genetically obese mice and d...

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Detalles Bibliográficos
Autores principales:	Shen, J, Tsoi, H, Liang, Q, Chu, E S H, Liu, D, Yu, A C-S, Chan, T F, Li, X, Sung, J J Y, Wong, V W S, Yu, J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153568/ https://www.ncbi.nlm.nih.gov/pubmed/27132506 http://dx.doi.org/10.1038/onc.2016.162

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