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Performance Evaluation and Online Realization of Data-driven Normalization Methods Used in LC/MS based Untargeted Metabolomics Analysis

In untargeted metabolomics analysis, several factors (e.g., unwanted experimental & biological variations and technical errors) may hamper the identification of differential metabolic features, which requires the data-driven normalization approaches before feature selection. So far, ≥16 normaliz...

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Detalles Bibliográficos
Autores principales: Li, Bo, Tang, Jing, Yang, Qingxia, Cui, Xuejiao, Li, Shuang, Chen, Sijie, Cao, Quanxing, Xue, Weiwei, Chen, Na, Zhu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153651/
https://www.ncbi.nlm.nih.gov/pubmed/27958387
http://dx.doi.org/10.1038/srep38881