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Comparative Systems Analyses Reveal Molecular Signatures of Clinically tested Vaccine Adjuvants

A better understanding of the mechanisms of action of human adjuvants could inform a rational development of next generation vaccines for human use. Here, we exploited a genome wide transcriptomics analysis combined with a systems biology approach to determine the molecular signatures induced by fou...

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Detalles Bibliográficos
Autores principales: Olafsdottir, Thorunn A., Lindqvist, Madelene, Nookaew, Intawat, Andersen, Peter, Maertzdorf, Jeroen, Persson, Josefine, Christensen, Dennis, Zhang, Yuan, Anderson, Jenna, Khoomrung, Sakda, Sen, Partho, Agger, Else Marie, Coler, Rhea, Carter, Darrick, Meinke, Andreas, Rappuoli, Rino, Kaufmann, Stefan H. E., Reed, Steven G., Harandi, Ali M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153655/
https://www.ncbi.nlm.nih.gov/pubmed/27958370
http://dx.doi.org/10.1038/srep39097