Cargando…
Comparative Systems Analyses Reveal Molecular Signatures of Clinically tested Vaccine Adjuvants
A better understanding of the mechanisms of action of human adjuvants could inform a rational development of next generation vaccines for human use. Here, we exploited a genome wide transcriptomics analysis combined with a systems biology approach to determine the molecular signatures induced by fou...
Autores principales: | Olafsdottir, Thorunn A., Lindqvist, Madelene, Nookaew, Intawat, Andersen, Peter, Maertzdorf, Jeroen, Persson, Josefine, Christensen, Dennis, Zhang, Yuan, Anderson, Jenna, Khoomrung, Sakda, Sen, Partho, Agger, Else Marie, Coler, Rhea, Carter, Darrick, Meinke, Andreas, Rappuoli, Rino, Kaufmann, Stefan H. E., Reed, Steven G., Harandi, Ali M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153655/ https://www.ncbi.nlm.nih.gov/pubmed/27958370 http://dx.doi.org/10.1038/srep39097 |
Ejemplares similares
-
Unraveling Molecular Signatures of Immunostimulatory Adjuvants in the Female Genital Tract through Systems Biology
por: Lindqvist, Madelene, et al.
Publicado: (2011) -
Metabolomics and Integrative Omics for the Development of Thai Traditional Medicine
por: Khoomrung, Sakda, et al.
Publicado: (2017) -
Molecular Signatures of a TLR4 Agonist-Adjuvanted HIV-1 Vaccine Candidate in Humans
por: Anderson, Jenna, et al.
Publicado: (2018) -
Different human vaccine adjuvants promote distinct antigen-independent immunological signatures tailored to different pathogens
por: Knudsen, Niels Peter H., et al.
Publicado: (2016) -
Deep learning facilitates multi-data type analysis and predictive biomarker discovery in cancer precision medicine
por: Mathema, Vivek Bhakta, et al.
Publicado: (2023)