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Population History and Natural Selection Shape Patterns of Genetic Variation in 132 Genes
Identifying regions of the human genome that have been targets of natural selection will provide important insights into human evolutionary history and may facilitate the identification of complex disease genes. Although the signature that natural selection imparts on DNA sequence variation is diffi...
Autores principales: | Akey, Joshua M, Eberle, Michael A, Rieder, Mark J, Carlson, Christopher S, Shriver, Mark D, Nickerson, Deborah A, Kruglyak, Leonid |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC515367/ https://www.ncbi.nlm.nih.gov/pubmed/15361935 http://dx.doi.org/10.1371/journal.pbio.0020286 |
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