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Validation of CoaBC as a Bactericidal Target in the Coenzyme A Pathway of Mycobacterium tuberculosis

[Image: see text] Mycobacterium tuberculosis relies on its own ability to biosynthesize coenzyme A to meet the needs of the myriad enzymatic reactions that depend on this cofactor for activity. As such, the essential pantothenate and coenzyme A biosynthesis pathways have attracted attention as targe...

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Detalles Bibliográficos
Autores principales:	Evans, Joanna C., Trujillo, Carolina, Wang, Zhe, Eoh, Hyungjin, Ehrt, Sabine, Schnappinger, Dirk, Boshoff, Helena I. M., Rhee, Kyu Y., Barry, Clifton E., Mizrahi, Valerie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2016
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153693/ https://www.ncbi.nlm.nih.gov/pubmed/27676316 http://dx.doi.org/10.1021/acsinfecdis.6b00150

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