Attenuation of chemokine receptor function and surface expression as an immunomodulatory strategy employed by human cytomegalovirus is linked to vGPCR US28

BACKGROUND: Some herpesviruses like human cytomegalovirus (HCMV) encode viral G protein-coupled receptors that cause reprogramming of cell signaling to facilitate dissemination of the virus, prevent immune surveillance and establish life-long latency. Human GPCRs are known to function in complex sig...

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Detalles Bibliográficos
Autores principales: Frank, Theresa, Reichel, Anna, Larsen, Olav, Stilp, Anne-Charlotte, Rosenkilde, Mette M., Stamminger, Thomas, Ozawa, Takeaki, Tschammer, Nuska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153698/
https://www.ncbi.nlm.nih.gov/pubmed/27955674
http://dx.doi.org/10.1186/s12964-016-0154-x

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