Carbamazepine-induced angioedema

Angioedema is a rare adverse reaction of carbamazepine, which causes localized tissue edema in submucosal and subcutaneous tissue mediated by histamine, serotonin, and kinins (bradykinin). We report a case of 34-year-old female who developed angioedema, 24 h after administration of carbamazepine for...

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Autores principales: Subramanian, Ansha, Adhimoolam, Mangaiarkkarasi, Gopalakrishnan, Senthil, Rajamohammed, Meher Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153889/
https://www.ncbi.nlm.nih.gov/pubmed/27999472
http://dx.doi.org/10.4103/0976-0105.189436
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author Subramanian, Ansha
Adhimoolam, Mangaiarkkarasi
Gopalakrishnan, Senthil
Rajamohammed, Meher Ali
author_facet Subramanian, Ansha
Adhimoolam, Mangaiarkkarasi
Gopalakrishnan, Senthil
Rajamohammed, Meher Ali
author_sort Subramanian, Ansha
collection PubMed
description Angioedema is a rare adverse reaction of carbamazepine, which causes localized tissue edema in submucosal and subcutaneous tissue mediated by histamine, serotonin, and kinins (bradykinin). We report a case of 34-year-old female who developed angioedema, 24 h after administration of carbamazepine for treating bipolar disorder. Patient's symptoms responded rapidly with antihistamine therapy and with the withdrawal of carbamazepine, the offending drug. Carbamazepine-induced angioedema is a life-threatening reaction which requires immediate treatment and monitoring in order to avoid morbidity and mortality.
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spelling pubmed-51538892016-12-20 Carbamazepine-induced angioedema Subramanian, Ansha Adhimoolam, Mangaiarkkarasi Gopalakrishnan, Senthil Rajamohammed, Meher Ali J Basic Clin Pharm Case Report Angioedema is a rare adverse reaction of carbamazepine, which causes localized tissue edema in submucosal and subcutaneous tissue mediated by histamine, serotonin, and kinins (bradykinin). We report a case of 34-year-old female who developed angioedema, 24 h after administration of carbamazepine for treating bipolar disorder. Patient's symptoms responded rapidly with antihistamine therapy and with the withdrawal of carbamazepine, the offending drug. Carbamazepine-induced angioedema is a life-threatening reaction which requires immediate treatment and monitoring in order to avoid morbidity and mortality. Medknow Publications & Media Pvt Ltd 2016-09 /pmc/articles/PMC5153889/ /pubmed/27999472 http://dx.doi.org/10.4103/0976-0105.189436 Text en Copyright: © Journal of Basic and Clinical Pharmacy http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Subramanian, Ansha
Adhimoolam, Mangaiarkkarasi
Gopalakrishnan, Senthil
Rajamohammed, Meher Ali
Carbamazepine-induced angioedema
title Carbamazepine-induced angioedema
title_full Carbamazepine-induced angioedema
title_fullStr Carbamazepine-induced angioedema
title_full_unstemmed Carbamazepine-induced angioedema
title_short Carbamazepine-induced angioedema
title_sort carbamazepine-induced angioedema
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153889/
https://www.ncbi.nlm.nih.gov/pubmed/27999472
http://dx.doi.org/10.4103/0976-0105.189436
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