Prognostic and predictive significance of long interspersed nucleotide element-1 methylation in advanced-stage colorectal cancer

BACKGROUND: Hypomethylation of Long Interspersed Nucleotide Element-1 (LINE-1) is associated with worse prognosis in colorectal cancer (CRC). However, little is known about the relevance of this marker for the prognosis and response to chemotherapy of metastatic and recurrent (advanced-stage) CRC. O...

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Detalles Bibliográficos
Autores principales: Kaneko, Mami, Kotake, Masanori, Bando, Hiroyuki, Yamada, Tetsuji, Takemura, Hirofumi, Minamoto, Toshinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154037/
https://www.ncbi.nlm.nih.gov/pubmed/27955637
http://dx.doi.org/10.1186/s12885-016-2984-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154037/
https://www.ncbi.nlm.nih.gov/pubmed/27955637
http://dx.doi.org/10.1186/s12885-016-2984-8

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