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Small GTPase Arl6 controls RH30 rhabdomyosarcoma cell growth through ciliogenesis and Hedgehog signaling

BACKGROUND: Rhabdomyosarcoma (RMS) originates from skeletal muscle precursors that fail to differentiate. Hedgehog (Hh) signaling and primary cilia contribute to the pathobiology of RMS. RESULTS: Here we showed ADP ribosylation factor like GTPase 6 (ARL6) localizes at the base of primary cilium, con...

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Detalles Bibliográficos
Autores principales:	Liu, Xiaotong, Shen, Qiuhong, Yu, Tingting, Huang, Huijie, Zhang, Ziyu, Ding, Jie, Tang, Ying, Xu, Ning, Yue, Shen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154108/ https://www.ncbi.nlm.nih.gov/pubmed/27999656 http://dx.doi.org/10.1186/s13578-016-0126-2

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