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Non-coding single nucleotide variants affecting estrogen receptor binding and activity

BACKGROUND: Estrogen receptor (ER) activity is critical for the development and progression of the majority of breast cancers. It is known that ER is differentially bound to DNA leading to transcriptomic and phenotypic changes in different breast cancer models. We investigated whether single nucleot...

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Detalles Bibliográficos
Autores principales:	Bahreini, Amir, Levine, Kevin, Santana-Santos, Lucas, Benos, Panayiotis V., Wang, Peilu, Andersen, Courtney, Oesterreich, Steffi, Lee, Adrian V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154163/ https://www.ncbi.nlm.nih.gov/pubmed/27964748 http://dx.doi.org/10.1186/s13073-016-0382-0

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