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HBV maintains electrostatic homeostasis by modulating negative charges from phosphoserine and encapsidated nucleic acids
Capsid assembly and stability of hepatitis B virus (HBV) core protein (HBc) particles depend on balanced electrostatic interactions between encapsidated nucleic acids and an arginine-rich domain (ARD) of HBc in the capsid interior. Arginine-deficient ARD mutants preferentially encapsidated spliced v...
Autores principales: | Su, Pei-Yi, Yang, Ching-Jen, Chu, Tien-Hua, Chang, Chih-Hsu, Chiang, Chiayn, Tang, Fan-Mei, Lee, Chih-Yin, Shih, Chiaho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154190/ https://www.ncbi.nlm.nih.gov/pubmed/27958343 http://dx.doi.org/10.1038/srep38959 |
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