Hepatic carcinoma-associated fibroblasts induce IDO-producing regulatory dendritic cells through IL-6-mediated STAT3 activation

Although carcinoma-associated fibroblasts (CAFs) in tumor microenvironments have a critical role in immune cell modulation, their effects on the generation of regulatory dendritic cells (DCs) are still unclear. In this study, we initially show that CAFs derived from hepatocellular carcinoma (HCC) tu...

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Detalles Bibliográficos
Autores principales: Cheng, J-t, Deng, Y-n, Yi, H-m, Wang, G-y, Fu, B-s, Chen, W-j, Liu, W, Tai, Y, Peng, Y-w, Zhang, Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154347/
https://www.ncbi.nlm.nih.gov/pubmed/26900950
http://dx.doi.org/10.1038/oncsis.2016.7

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