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Epidemiological and Clinical Features of Severe Fever with Thrombocytopenia Syndrome during an Outbreak in South Korea, 2013–2015
Since the first reported case of severe fever with thrombocytopenia syndrome (SFTS) in South Korea in 2013, between 2013 and 2015, we collected 1,697 serum samples from suspected patients who experienced symptoms of SFTS. We performed reverse transcriptase polymerase chain reaction using total RNA e...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The American Society of Tropical Medicine and Hygiene
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154450/ https://www.ncbi.nlm.nih.gov/pubmed/27928084 http://dx.doi.org/10.4269/ajtmh.16-0251 |
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author | Park, Sun-Whan Ryou, Jungsang Choi, Woo-Young Han, Myung-Guk Lee, Won-Ja |
author_facet | Park, Sun-Whan Ryou, Jungsang Choi, Woo-Young Han, Myung-Guk Lee, Won-Ja |
author_sort | Park, Sun-Whan |
collection | PubMed |
description | Since the first reported case of severe fever with thrombocytopenia syndrome (SFTS) in South Korea in 2013, between 2013 and 2015, we collected 1,697 serum samples from suspected patients who experienced symptoms of SFTS. We performed reverse transcriptase polymerase chain reaction using total RNA extracted from the patients' sera. When viral RNA was detected in the sera, SFTS was diagnosed. Among the 1,697 samples, 170 were positive for SFTS virus. We then analyzed the epidemiologic features of these 170 cases. As a result, we found that the annual number of cases increased steadily. However, the annual case fatality rate exhibited a downward trend. The majority of patients were aged ≥ 60 years, and most cases occurred during May–October in the eastern and southern parts of the country. These results may be useful for effective SFTS control by describing the clinical and epidemiologic features of the disease in South Korea. |
format | Online Article Text |
id | pubmed-5154450 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The American Society of Tropical Medicine and Hygiene |
record_format | MEDLINE/PubMed |
spelling | pubmed-51544502016-12-19 Epidemiological and Clinical Features of Severe Fever with Thrombocytopenia Syndrome during an Outbreak in South Korea, 2013–2015 Park, Sun-Whan Ryou, Jungsang Choi, Woo-Young Han, Myung-Guk Lee, Won-Ja Am J Trop Med Hyg Articles Since the first reported case of severe fever with thrombocytopenia syndrome (SFTS) in South Korea in 2013, between 2013 and 2015, we collected 1,697 serum samples from suspected patients who experienced symptoms of SFTS. We performed reverse transcriptase polymerase chain reaction using total RNA extracted from the patients' sera. When viral RNA was detected in the sera, SFTS was diagnosed. Among the 1,697 samples, 170 were positive for SFTS virus. We then analyzed the epidemiologic features of these 170 cases. As a result, we found that the annual number of cases increased steadily. However, the annual case fatality rate exhibited a downward trend. The majority of patients were aged ≥ 60 years, and most cases occurred during May–October in the eastern and southern parts of the country. These results may be useful for effective SFTS control by describing the clinical and epidemiologic features of the disease in South Korea. The American Society of Tropical Medicine and Hygiene 2016-12-07 /pmc/articles/PMC5154450/ /pubmed/27928084 http://dx.doi.org/10.4269/ajtmh.16-0251 Text en ©The American Society of Tropical Medicine and Hygiene This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Articles Park, Sun-Whan Ryou, Jungsang Choi, Woo-Young Han, Myung-Guk Lee, Won-Ja Epidemiological and Clinical Features of Severe Fever with Thrombocytopenia Syndrome during an Outbreak in South Korea, 2013–2015 |
title | Epidemiological and Clinical Features of Severe Fever with Thrombocytopenia Syndrome during an Outbreak in South Korea, 2013–2015 |
title_full | Epidemiological and Clinical Features of Severe Fever with Thrombocytopenia Syndrome during an Outbreak in South Korea, 2013–2015 |
title_fullStr | Epidemiological and Clinical Features of Severe Fever with Thrombocytopenia Syndrome during an Outbreak in South Korea, 2013–2015 |
title_full_unstemmed | Epidemiological and Clinical Features of Severe Fever with Thrombocytopenia Syndrome during an Outbreak in South Korea, 2013–2015 |
title_short | Epidemiological and Clinical Features of Severe Fever with Thrombocytopenia Syndrome during an Outbreak in South Korea, 2013–2015 |
title_sort | epidemiological and clinical features of severe fever with thrombocytopenia syndrome during an outbreak in south korea, 2013–2015 |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154450/ https://www.ncbi.nlm.nih.gov/pubmed/27928084 http://dx.doi.org/10.4269/ajtmh.16-0251 |
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