Dual Therapeutic Action of a Neutralizing Anti-FGF2 Aptamer in Bone Disease and Bone Cancer Pain

Fibroblast growth factor 2 (FGF2) plays a crucial role in bone remodeling and disease progression. However, the potential of FGF2 antagonists for treatment of patients with bone diseases has not yet been explored. Therefore, we generated a novel RNA aptamer, APT-F2, specific for human FGF2 and chara...

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Detalles Bibliográficos
Autores principales: Jin, Ling, Nonaka, Yosuke, Miyakawa, Shin, Fujiwara, Masatoshi, Nakamura, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154475/
https://www.ncbi.nlm.nih.gov/pubmed/27506449
http://dx.doi.org/10.1038/mt.2016.158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154475/
https://www.ncbi.nlm.nih.gov/pubmed/27506449
http://dx.doi.org/10.1038/mt.2016.158

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