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Dual Roles for Membrane Association of Drosophila Axin in Wnt Signaling

Deregulation of the Wnt signal transduction pathway underlies numerous congenital disorders and cancers. Axin, a concentration-limiting scaffold protein, facilitates assembly of a “destruction complex” that prevents signaling in the unstimulated state and a plasma membrane-associated “signalosome” t...

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Detalles Bibliográficos
Autores principales:	Wang, Zhenghan, Tacchelly-Benites, Ofelia, Yang, Eungi, Ahmed, Yashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154497/ https://www.ncbi.nlm.nih.gov/pubmed/27959917 http://dx.doi.org/10.1371/journal.pgen.1006494

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