Cargando…

Stabilization of Human Serum Albumin by the Binding of Phycocyanobilin, a Bioactive Chromophore of Blue-Green Alga Spirulina: Molecular Dynamics and Experimental Study

Phycocyanobilin (PCB) binds with high affinity (2.2 x 10(6) M(-1) at 25°C) to human serum albumin (HSA) at sites located in IB and IIA subdomains. The aim of this study was to examine effects of PCB binding on protein conformation and stability. Using 300 ns molecular dynamics (MD) simulations, UV-V...

Descripción completa

Detalles Bibliográficos
Autores principales:	Radibratovic, Milica, Minic, Simeon, Stanic-Vucinic, Dragana, Nikolic, Milan, Milcic, Milos, Cirkovic Velickovic, Tanja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154526/ https://www.ncbi.nlm.nih.gov/pubmed/27959940 http://dx.doi.org/10.1371/journal.pone.0167973

Ejemplares similares

The Bioactivities of Phycocyanobilin from Spirulina
por: Li, Yi
Publicado: (2022)

Dyeing Non-Recyclable Polyethylene Plastic with Photoacid Phycocyanobilin from Spirulina Algae: Ultrafast Photoluminescence Studies
por: Alhefeiti, Maryam, et al.
Publicado: (2022)

Near-Infrared Markers based on Bacterial Phytochromes with Phycocyanobilin as a Chromophore
por: Stepanenko, Olesya V., et al.
Publicado: (2019)

Conformational stability of digestion-resistant peptides of peanut conglutins reveals the molecular basis of their allergenicity
por: Apostolovic, Danijela, et al.
Publicado: (2016)

Ultrasensitive Quantification of Crustacean Tropomyosin by Immuno-PCR
por: Radomirović, Mirjana, et al.
Publicado: (2023)

Pressurized Liquid Extraction of a Phycocyanobilin Chromophore and Its Reconstitution with a Cyanobacteriochrome Photosensor for Efficient Isotopic Labeling
por: Kamo, Takanari, et al.
Publicado: (2021)

Food Antioxidants and Their Interaction with Human Proteins
por: Nedić, Olgica, et al.
Publicado: (2023)

Molecular Mechanisms of Possible Action of Phenolic Compounds in COVID-19 Protection and Prevention
por: Gligorijevic, Nikola, et al.
Publicado: (2021)

Role of Resveratrol in Prevention and Control of Cardiovascular Disorders and Cardiovascular Complications Related to COVID-19 Disease: Mode of Action and Approaches Explored to Increase Its Bioavailability
por: Gligorijević, Nikola, et al.
Publicado: (2021)

Elucidating the origins of phycocyanobilin biosynthesis and phycobiliproteins
por: Rockwell, Nathan C., et al.
Publicado: (2023)

Glycation of the Major Milk Allergen β‐Lactoglobulin Changes Its Allergenicity by Alterations in Cellular Uptake and Degradation
por: Perusko, Marija, et al.
Publicado: (2018)

Study the antioxidant effects of blue-green algae Spirulina extract on ROS and MDA production in human lung cancer cells
por: Tajvidi, Elham, et al.
Publicado: (2021)

Blue-Green Algae (Spirulina platensis) Alleviates the Negative Impact of Heat Stress on Broiler Production Performance and Redox Status
por: Moustafa, Eman S., et al.
Publicado: (2021)

Proteomic Profiling of Major Peanut Allergens and Their Post-Translational Modifications Affected by Roasting
por: Đukić, Teodora, et al.
Publicado: (2022)

The value of blue-green algae (Spirulina platensis) as a nutritive supplement and toxicant against almond moth [Cadra cautella (Lepidoptera: Pyralidae)]
por: Al-Qahtani, Wahidah H.
Publicado: (2021)

Expression, purification and immunological characterization of recombinant nucleocapsid protein fragment from SARS-CoV-2
por: Djukic, Teodora, et al.
Publicado: (2021)

The Effect of Storage and Pasteurization (Thermal and High-Pressure) Conditions on the Stability of Phycocyanobilin and Phycobiliproteins
por: Shkolnikov Lozober, Hani, et al.
Publicado: (2023)

Chromophore Deprotonation State Alters the Optical Properties of Blue Chromoprotein
por: Chiang, Cheng-Yi, et al.
Publicado: (2015)

Algae Supplementation for Exercise Performance: Current Perspectives and Future Directions for Spirulina and Chlorella
por: Gurney, Tom, et al.
Publicado: (2022)

Photophysics and Dihedral Freedom of the Chromophore in Yellow, Blue, and Green Fluorescent Protein
por: Megley, Colleen M., et al.
Publicado: (2008)

An Enhanced Monomeric Blue Fluorescent Protein with the High Chemical Stability of the Chromophore
por: Subach, Oksana M., et al.
Publicado: (2011)

A metal-free blue chromophore derived from plant pigments
por: Freitas-Dörr, B. C., et al.
Publicado: (2020)

Enhancement of phycocyanobilin biosynthesis in Escherichia coli by strengthening the supply of precursor and artificially self-assembly complex
por: Wang, Yuqi, et al.
Publicado: (2023)

Blue-Coloured Highly Efficient Dye-Sensitized Solar Cells by Implementing the Diketopyrrolopyrrole Chromophore
por: Yum, Jun-Ho, et al.
Publicado: (2013)

C-Phycocyanin and Phycocyanobilin as Remyelination Therapies for Enhancing Recovery in Multiple Sclerosis and Ischemic Stroke: A Preclinical Perspective
por: Pentón-Rol, Giselle, et al.
Publicado: (2018)

Evaluation and Predictive Modeling of Removal Condition for Bioadsorption of Indigo Blue Dye by Spirulina platensis
por: Robledo-Padilla, Felipe, et al.
Publicado: (2020)

DELAYED LIGHT PRODUCTION BY BLUE-GREEN ALGAE, RED ALGAE, AND PURPLE BACTERIA
por: Arnold, William, et al.
Publicado: (1956)

ELECTRON MICROSCOPE STUDIES ON BLUE-GREEN ALGAE
por: Ris, Hans, et al.
Publicado: (1961)

The Use of Mushrooms and Spirulina Algae as Supplements to Prevent Growth Inhibition in a Pre-Clinical Model for an Unbalanced Diet
por: Sides, Roni, et al.
Publicado: (2021)

Supplementation with Phycocyanobilin, Citrulline, Taurine, and Supranutritional Doses of Folic Acid and Biotin—Potential for Preventing or Slowing the Progression of Diabetic Complications
por: McCarty, Mark F.
Publicado: (2017)

Effect of using spirulina algae methyl ester on the performance of a diesel engine with changing compression ratio: an experimental investigation
por: Al-Dawody, Mohamed F., et al.
Publicado: (2022)

The effects of Phycocyanobilin on experimental arthritis involve the reduction in nociception and synovial neutrophil infiltration, inhibition of cytokine production, and modulation of the neuronal proteome
por: Marín-Prida, Javier, et al.
Publicado: (2023)

Photophysical and Electro-Optical Properties of Copolymers Bearing Blue and Red Chromophores for Single-Layer White OLEDs
por: Tselekidou, Despoina, et al.
Publicado: (2021)

INTERNAL CONVERSION IN THE PHOTOSYNTHETIC MECHANISM OF BLUE-GREEN ALGAE
por: Arnold, William, et al.
Publicado: (1950)

PHYCOBILISOMES OF THE THERMOPHILIC BLUE-GREEN ALGA SYNECHOCOCCUS LIVIDUS
por: Edwards, Mercedes R., et al.
Publicado: (1971)

GAS VACUOLES : Light Shielding in Blue-Green Algae
por: Waaland, J. Robert, et al.
Publicado: (1971)

Potency of spirulina (Spirulina platensis) on arsenic-induced lipid peroxidation in rat
por: Khair, Abul, et al.
Publicado: (2021)

Microbiota and Cyanotoxin Content of Retail Spirulina Supplements and Spirulina Supplemented Foods
por: Rhoades, Jonathan, et al.
Publicado: (2023)

Human Hemoglobin and Antipsychotics Clozapine, Ziprasidone and Sertindole: Friends or Foes?
por: Platanić Arizanović, Lena, et al.
Publicado: (2023)

C-Phycocyanin-derived Phycocyanobilin as a Potential Nutraceutical Approach for Major Neurodegenerative Disorders and COVID-19-induced Damage to the Nervous System
por: Pentón-Rol, Giselle, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4svilej9tc4pbvjgc2ba8oi3tb