Capture-stabilize approach for membrane protein SPR assays

Measuring the binding kinetics of antibodies to intact membrane proteins by surface plasmon resonance has been challenging largely because of the inherent difficulties in capturing membrane proteins on chip surfaces while retaining their native conformation. Here we describe a method in which His-ta...

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Detalles Bibliográficos
Autores principales: Chu, Ruiyin, Reczek, David, Brondyk, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154539/
https://www.ncbi.nlm.nih.gov/pubmed/25484112
http://dx.doi.org/10.1038/srep07360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154539/
https://www.ncbi.nlm.nih.gov/pubmed/25484112
http://dx.doi.org/10.1038/srep07360

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