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Homogeneous and digital proximity ligation assays for the detection of Clostridium difficile toxins A and B

BACKGROUND: The proximity ligation assay (PLA) detects proteins via their interaction with pairs of proximity probes, which are antibodies coupled to noncomplementary DNA oligonucleotides. The binding of both proximity probes to their epitopes on the target protein brings the oligonucleotides togeth...

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Detalles Bibliográficos
Autores principales: Dhillon, Harvinder S., Johnson, Gemma, Shannon, Mark, Greenwood, Christina, Roberts, Doug, Bustin, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154635/
https://www.ncbi.nlm.nih.gov/pubmed/27990343
http://dx.doi.org/10.1016/j.bdq.2016.06.003