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Homogeneous and digital proximity ligation assays for the detection of Clostridium difficile toxins A and B
BACKGROUND: The proximity ligation assay (PLA) detects proteins via their interaction with pairs of proximity probes, which are antibodies coupled to noncomplementary DNA oligonucleotides. The binding of both proximity probes to their epitopes on the target protein brings the oligonucleotides togeth...
Autores principales: | Dhillon, Harvinder S., Johnson, Gemma, Shannon, Mark, Greenwood, Christina, Roberts, Doug, Bustin, Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154635/ https://www.ncbi.nlm.nih.gov/pubmed/27990343 http://dx.doi.org/10.1016/j.bdq.2016.06.003 |
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