Epithelial ovarian cancer inherent resistance: May the pleiotropic interaction between reduced immunosurveillance and drug-resistant cells play a key role?

• Cancer cells may have inherent chemoresistance which allows an indefinite expansion. • Transformed ovarian epithelial cells may undergo an immunoediting process. • Immunoedited ovarian cancer drug-resistant cells escape first-line chemotherapy.

Detalles Bibliográficos
Autores principales: Laganà, Antonio Simone, Sofo, Vincenza, Vitale, Salvatore Giovanni, Triolo, Onofrio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154672/
https://www.ncbi.nlm.nih.gov/pubmed/27995176
http://dx.doi.org/10.1016/j.gore.2016.09.004
Descripción
Sumario:• Cancer cells may have inherent chemoresistance which allows an indefinite expansion. • Transformed ovarian epithelial cells may undergo an immunoediting process. • Immunoedited ovarian cancer drug-resistant cells escape first-line chemotherapy.

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