Epithelial ovarian cancer inherent resistance: May the pleiotropic interaction between reduced immunosurveillance and drug-resistant cells play a key role?

• Cancer cells may have inherent chemoresistance which allows an indefinite expansion. • Transformed ovarian epithelial cells may undergo an immunoediting process. • Immunoedited ovarian cancer drug-resistant cells escape first-line chemotherapy.

Detalles Bibliográficos
Autores principales: Laganà, Antonio Simone, Sofo, Vincenza, Vitale, Salvatore Giovanni, Triolo, Onofrio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154672/
https://www.ncbi.nlm.nih.gov/pubmed/27995176
http://dx.doi.org/10.1016/j.gore.2016.09.004
_version_ 1782474902567124992
author Laganà, Antonio Simone
Sofo, Vincenza
Vitale, Salvatore Giovanni
Triolo, Onofrio
author_facet Laganà, Antonio Simone
Sofo, Vincenza
Vitale, Salvatore Giovanni
Triolo, Onofrio
author_sort Laganà, Antonio Simone
collection PubMed
description • Cancer cells may have inherent chemoresistance which allows an indefinite expansion. • Transformed ovarian epithelial cells may undergo an immunoediting process. • Immunoedited ovarian cancer drug-resistant cells escape first-line chemotherapy.
format Online
Article
Text
id pubmed-5154672
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-51546722016-12-19 Epithelial ovarian cancer inherent resistance: May the pleiotropic interaction between reduced immunosurveillance and drug-resistant cells play a key role? Laganà, Antonio Simone Sofo, Vincenza Vitale, Salvatore Giovanni Triolo, Onofrio Gynecol Oncol Rep Correspondence • Cancer cells may have inherent chemoresistance which allows an indefinite expansion. • Transformed ovarian epithelial cells may undergo an immunoediting process. • Immunoedited ovarian cancer drug-resistant cells escape first-line chemotherapy. Elsevier 2016-09-19 /pmc/articles/PMC5154672/ /pubmed/27995176 http://dx.doi.org/10.1016/j.gore.2016.09.004 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Correspondence
Laganà, Antonio Simone
Sofo, Vincenza
Vitale, Salvatore Giovanni
Triolo, Onofrio
Epithelial ovarian cancer inherent resistance: May the pleiotropic interaction between reduced immunosurveillance and drug-resistant cells play a key role?
title Epithelial ovarian cancer inherent resistance: May the pleiotropic interaction between reduced immunosurveillance and drug-resistant cells play a key role?
title_full Epithelial ovarian cancer inherent resistance: May the pleiotropic interaction between reduced immunosurveillance and drug-resistant cells play a key role?
title_fullStr Epithelial ovarian cancer inherent resistance: May the pleiotropic interaction between reduced immunosurveillance and drug-resistant cells play a key role?
title_full_unstemmed Epithelial ovarian cancer inherent resistance: May the pleiotropic interaction between reduced immunosurveillance and drug-resistant cells play a key role?
title_short Epithelial ovarian cancer inherent resistance: May the pleiotropic interaction between reduced immunosurveillance and drug-resistant cells play a key role?
title_sort epithelial ovarian cancer inherent resistance: may the pleiotropic interaction between reduced immunosurveillance and drug-resistant cells play a key role?
topic Correspondence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154672/
https://www.ncbi.nlm.nih.gov/pubmed/27995176
http://dx.doi.org/10.1016/j.gore.2016.09.004
work_keys_str_mv AT laganaantoniosimone epithelialovariancancerinherentresistancemaythepleiotropicinteractionbetweenreducedimmunosurveillanceanddrugresistantcellsplayakeyrole
AT sofovincenza epithelialovariancancerinherentresistancemaythepleiotropicinteractionbetweenreducedimmunosurveillanceanddrugresistantcellsplayakeyrole
AT vitalesalvatoregiovanni epithelialovariancancerinherentresistancemaythepleiotropicinteractionbetweenreducedimmunosurveillanceanddrugresistantcellsplayakeyrole
AT trioloonofrio epithelialovariancancerinherentresistancemaythepleiotropicinteractionbetweenreducedimmunosurveillanceanddrugresistantcellsplayakeyrole

Ejemplares similares