Cargando…
Knockdown of EWSR1/FLI1 expression alters the transcriptome of Ewing sarcoma cells in vitro
Ewing sarcoma breakpoint region 1 (EWSR1) fusion with Friend leukemia integration 1 transcription factor (FLI1) induced by a translocation of chromosome 11 with 22 contributes to Ewing sarcoma development. To date, the precise molecular mechanisms about EWSR1/FLI1 involving in Ewing sarcoma developm...
Autores principales: | Wang, Jihan, Jiang, Wenyan, Yan, Yuzhu, Chen, Chu, Yu, Yan, Wang, Biao, Zhao, Heping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154700/ https://www.ncbi.nlm.nih.gov/pubmed/28008375 http://dx.doi.org/10.1016/j.jbo.2016.05.006 |
Ejemplares similares
-
High Specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG Positive Ewing Sarcoma
por: Orth, Martin F., et al.
Publicado: (2020) -
Therapeutic Potential of EWSR1–FLI1 Inactivation by CRISPR/Cas9 in Ewing Sarcoma
por: Cervera, Saint T., et al.
Publicado: (2021) -
Chromosomal localization of Ewing sarcoma EWSR1/FLI1 protein promotes the induction of aneuploidy
por: Park, Hyewon, et al.
Publicado: (2020) -
Selective inhibition of HDAC6 regulates expression of the oncogenic driver EWSR1-FLI1 through the EWSR1 promoter in Ewing sarcoma
por: García-Domínguez, Daniel J., et al.
Publicado: (2021) -
Reconstruction of Ewing Sarcoma Developmental Context from Mass-Scale Transcriptomics Reveals Characteristics of EWSR1-FLI1 Permissibility
por: Miller, Henry E., et al.
Publicado: (2020)